Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20381251 | 0.84 | ALOX5 (0.48) | ALOX5PTGS2GPR84TSHRTYR | |
| SCHEMBL20381226 | 0.82 | ALOX5 (0.47) | ALOX5PTGS2GPR84TSHRMEN1 | |
| SCHEMBL16050406 | 0.81 | ALDH1A1 (0.57) | ALOX5PTGS2GPR84TSHRTHRA | |
| SCHEMBL19166810 | 0.81 | GPR84 (0.49) | ALOX5PTGS2GPR84TSHRTYR | |
| SCHEMBL28542042 | 0.80 | ALDH1A1 (0.56) | ALOX5PTGS2GPR84TSHRTHRA | |
| SCHEMBL16050932 | 0.80 | ALDH1A1 (0.59) | ALOX5PTGS2GPR84TSHRTHRA | |
| SCHEMBL19166232 | 0.80 | GPR84 (0.50) | ALOX5PTGS2GPR84TSHRTYR | |
| SCHEMBL17678362 | 0.79 | GPR84 (0.50) | ALOX5PTGS2GPR84ALDH1A1BID | |
| SCHEMBL30003253 | 0.79 | NR4A1 (0.45) | ALOX5PTGS2GPR84HTTEGFR | |
| SCHEMBL28538520 | 0.78 | ALDH1A1 (0.57) | ALOX5PTGS2GPR84TSHRTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970089-B1 | SUBSTITUTED AROMATIC COMPOUNDS | PROMETIC PHARMA SMT LTD (GB) | 2019-05-08 | — | — | EP | disclosed |