SCHEMBL20982033

SCHEMBL20982033

CO[Si](C)(C)CCCN(CCC[Si](C)(C)OC)C(=O)N(Cc1ccco1)[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.41
▸ POLB P06746 2/20 0.40
▸ TSHR P16473 3/20 0.40
▸ ALOX5 P09917 1/20 0.39
▸ ALDH1A1 P00352 1/20 0.39
▸ MAPK1 P28482 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20982045 0.90 MAPT (0.41) MAPTPOLBTSHRALOX5ALDH1A1
SCHEMBL20982044 0.90 MAPT (0.43) MAPTPOLBTSHRALOX5ALDH1A1
SCHEMBL20982057 0.88 POLB (0.41) MAPTPOLBALDH1A1
SCHEMBL20982052 0.83 POLB (0.41) MAPTPOLBALDH1A1
SCHEMBL20982032 0.83 POLB (0.41) MAPTPOLBALDH1A1
SCHEMBL20982046 0.79 MAPT (0.38) MAPTPOLBTSHRALOX5ALDH1A1
SCHEMBL20982053 0.75 POLB (0.39) MAPTPOLBALDH1A1
SCHEMBL20982038 0.71 ALOX5 (0.50) MAPTPOLBTSHRALOX5ALDH1A1
SCHEMBL20982039 0.67 RIPK1 (0.44) MAPTPOLBTSHRALOX5ALDH1A1
SCHEMBL21393181 0.66 MAPK1 (0.66) MAPTPOLBTSHRALOX5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10913805-B2 Modifier, method for preparing the same, and modified conjugated diene-based polymer including the same LG CHEM, LTD. 2021-02-09 — — US disclosed
EP-3486279-B1 MODIFIER, METHOD FOR PREPARING SAME, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPRISING SAME LG CHEMICAL LTD (KR) 2020-09-09 — — EP disclosed
US-20190177457-A1 Modifier, Method For Preparing The Same, And Modified Conjugated Diene-Based Polymer Including The Same LG CHEM, LTD. (KR) 2019-06-13 — — US disclosed
EP-3486279-A1 MODIFIER, METHOD FOR PREPARING SAME, AND MODIFIED CONJUGATED DIENE-BASED POLYMER COMPRISING SAME LG Chem, Ltd. (KR) 2019-05-22 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177457-A1 Modifier, Method For Preparing The Same, And Modified Conjugated Diene-Based Polymer Including The Same FDFT1, DHPS, ALOX5 MAPT 2090/4885POLB 2231/4885TSHR 3955/4885
US-10913805-B2 Modifier, method for preparing the same, and modified conjugated diene-based polymer including the same FDFT1, DHPS, ALOX5 MAPT 2090/4885POLB 2231/4885TSHR 3955/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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