SCHEMBL20982137

SCHEMBL20982137

CC1=NOC(c2cc(N)c(Cl)c(C(=O)Oc3ccccc3)n2)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.36
FAAH O00519 7/20 0.33
MAPT P10636 4/20 0.33
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
PTPN1 P18031 1/20 0.33
KMT2A Q03164 3/20 0.33
WDR5 P61964 2/20 0.33
RBBP5 Q15291 1/20 0.33
ASH2L Q9UBL3 1/20 0.33
MEN1 O00255 1/20 0.32
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
SLC6A2 P23975 1/20 0.32
PDE4A P27815 1/20 0.32
ADRA1A P35348 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20996703 0.91 FAAH (0.34) IDO1FAAHMAPTPOLBPTPN1
SCHEMBL20955452 0.90 FAAH (0.33) IDO1FAAHMAPTPTPN1LMNA
SCHEMBL20982142 0.90 FAAH (0.33) IDO1FAAHMAPTTDP1POLB
Lithium Ion SCHEMBL20996700 0.85 FAAH (0.31) FAAH
SCHEMBL20955607 0.85 NQO2 (0.36) MAPTSMN1; SMN2
SCHEMBL23468841 0.84 FAAH (0.33) FAAHMAPTLMNATP53CYP3A4
SCHEMBL20955402 0.84 TDP1 (0.34) TDP1CYP3A4
SCHEMBL20982089 0.83 MAPT (0.36) MAPTKMT2AMEN1LMNATP53
SCHEMBL20981710 0.82 ALDH1A1 (0.34) LMNASMN1; SMN2
SCHEMBL23468874 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3479696-B1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE MOGHU RES CENTER LTD (KR) 2021-06-09 EP disclosed
EP-3479696-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE Moghu Research Center Ltd. (KR) 2019-05-08 EP disclosed