SCHEMBL20955402

SCHEMBL20955402

CC1=NOC(c2cc(N)c(Cl)c(C(=O)O)n2)C1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.34
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23468874 0.88
SCHEMBL20955607 0.88 NQO2 (0.36)
SCHEMBL20955365 0.88 TDP1 (0.34) TDP1CYP3A4
SCHEMBL20955347 0.87 LMNA (0.38) TDP1CYP3A4
SCHEMBL28567235 0.86 LMNA (0.37) TDP1CYP3A4
SCHEMBL28578629 0.86 LMNA (0.37) TDP1CYP3A4
SCHEMBL20981867 0.86 TDP1 (0.35) TDP1CYP3A4
SCHEMBL20982089 0.86 MAPT (0.36)
SCHEMBL20981710 0.85 ALDH1A1 (0.34)
SCHEMBL20982137 0.84 IDO1 (0.36) TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3479696-B1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE MOGHU RES CENTER LTD (KR) 2021-06-09 EP claimed
CN-109561682-B Pyridines comprising an isoxazoline ring and their use as herbicides 牧牛研究所株式会社 2021-05-11 CN claimed
US-20190159450-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE MOGHU RESEARCH CENTER LTD. (KR) 2019-05-30 US claimed
EP-3479696-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE Moghu Research Center Ltd. (KR) 2019-05-08 EP claimed
EP-3479696-B1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE MOGHU RES CENTER LTD (KR) 2021-06-09 EP disclosed
EP-3479696-B1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE MOGHU RES CENTER LTD (KR) 2021-06-09 EP disclosed
CN-109561682-B Pyridines comprising an isoxazoline ring and their use as herbicides 牧牛研究所株式会社 2021-05-11 CN disclosed
US-20190159450-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE MOGHU RESEARCH CENTER LTD. (KR) 2019-05-30 US disclosed
US-20190159450-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE MOGHU RESEARCH CENTER LTD. (KR) 2019-05-30 US disclosed
EP-3479696-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE Moghu Research Center Ltd. (KR) 2019-05-08 EP disclosed
EP-3479696-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING, AND USE THEREOF AS HERBICIDE Moghu Research Center Ltd. (KR) 2019-05-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190159450-A1 PYRIDINE-BASED COMPOUND INCLUDING ISOXAZOLINE RING AND USE THEREOF AS HERBICIDE CYP4X1, CYP3A7, IDH2 TDP1 2636/4885CYP3A4 45/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.