SCHEMBL20982802

SCHEMBL20982802

C#CCOc1cc(C=O)ccc1C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.42
LMNA P02545 1/20 0.42
ALDH1A1 P00352 5/20 0.41
TSHR P16473 2/20 0.41
PDE4B Q07343 1/20 0.40
HPGD P15428 4/20 0.39
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TRIM24 O15164 1/20 0.38
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
MAOB P27338 2/20 0.37
CA12 O43570 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
POLB P06746 2/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22160270 0.84 FDPS (0.47) FDPSLMNAALDH1A1TSHRHPGD
SCHEMBL29470912 0.82 TSHR (0.42) LMNAALDH1A1TSHRPDE4BHPGD
SCHEMBL26082494 0.82 HPGD (0.41) LMNAALDH1A1TSHRHPGDKMT2A
SCHEMBL29955556 0.82 MAOB (0.39) LMNAALDH1A1TSHRPDE4BHPGD
SCHEMBL16272278 0.82 PDE4B (0.45) FDPSLMNAALDH1A1TSHRPDE4B
SCHEMBL15240136 0.82 HPGD (0.55) LMNAALDH1A1TSHRHPGDKMT2A
SCHEMBL1891324 0.82 ALDH1A1 (0.64) FDPSLMNAALDH1A1TSHRPDE4B
SCHEMBL19640150 0.82 HPGD (0.41) LMNAALDH1A1TSHRHPGDKMT2A
SCHEMBL433948 0.81 ALDH1A1 (0.64) FDPSLMNAALDH1A1TSHRPDE4B
SCHEMBL1231147 0.81 FDPS (0.69) FDPSLMNAALDH1A1TSHRPDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019575-A Covalent organic framework films, methods and uses thereof 新加坡国立大学 2024-05-10 CN claimed
CN-117871858-A Protein colorimetric analysis method based on polypeptide functionalized covalent organic frameworks 南京大学 2024-04-12 CN claimed
CN-115301216-B High internal phase emulsion polymerization grading porous capillary monolithic column and preparation method and application thereof 武汉大学 2024-04-05 CN claimed
CN-117101617-A Bonding type imine three-component spherical COF-based stationary phase and preparation method and application thereof 华南师大(清远)科技创新研究院有限公司 2023-11-24 CN claimed
CN-116786089-A Boric acid functionalized covalent organic framework microcapsule adsorbent and preparation method and application thereof 南通三圣石墨设备科技股份有限公司 2023-09-22 CN claimed
CN-116660523-A Nano-enzyme-based hypersensitive circulating tumor cell detection method 云南大学 2023-08-29 CN claimed
CN-114539547-A Covalent Organic Framework (COF) nanoparticles and preparation method thereof 中国科学院长春应用化学研究所 2022-05-27 CN claimed
CN-113234203-B Covalent organic framework material and preparation method and application thereof 华南理工大学 2022-03-29 CN claimed
CN-114209833-A Sound-sensitive agent based on porphyrin-based covalent organic framework, and preparation method and application thereof 中国科学院长春应用化学研究所 2022-03-22 CN claimed
CN-112679781-B Method for realizing efficient gas separation of COFs (carbon-on-glass) thin film through post-synthesis modification 北京理工大学 2021-09-21 CN claimed
CN-112226143-B High-electromagnetic-wave-reflection unmanned automobile coating composition and application thereof 厦门大学 2021-08-24 CN claimed
CN-113234203-A Covalent organic framework material and preparation method and application thereof 华南理工大学 2021-08-10 CN claimed
CN-110128672-B Synthesis method of covalent organic framework compound modified by side chain 北京乐风动力能源技术有限公司 2021-05-25 CN claimed
CN-112679781-A Method for realizing efficient gas separation of COFs (carbon-on-glass) thin film through post-synthesis modification 北京理工大学 2021-04-20 CN claimed
CN-112226143-A High-electromagnetic-wave-reflection unmanned automobile coating composition and application thereof 厦门大学 2021-01-15 CN claimed
CN-121574326-A Fluorescent array sensor for detecting multi-generation energetic compounds, and preparation method and application thereof 南京理工大学 2026-02-27 CN disclosed
CN-118019575-A Covalent organic framework films, methods and uses thereof 新加坡国立大学 2024-05-10 CN disclosed
CN-110698684-A Covalent organic framework material with diarylethene photonic switch and synthetic method and application thereof 山东师范大学 2020-01-17 CN disclosed
US-20190152924-A1 BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2019-05-23 US disclosed
US-20190152924-A1 BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2019-05-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190152924-A1 BIS-BENZIMIDAZOLE COMPOUNDS AND METHODS OF USING THE SAME HNRNPH1, HNRNPH3, HNRNPUL2 FDPS 1912/4885LMNA 963/4885ALDH1A1 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.