SCHEMBL20983813

SCHEMBL20983813

O=C(OC(C(F)(F)F)C(F)(F)F)N1CCc2c(Br)cccc2C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ABHD6 Q9BV23 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20983823 0.90 ABHD6 (1.00) ABHD6
SCHEMBL20983867 0.89 ABHD6 (1.00) ABHD6
SCHEMBL20983768 0.86 ABHD6 (1.00) ABHD6
SCHEMBL20983766 0.86 ABHD6 (1.00) ABHD6
SCHEMBL20983833 0.83 ABHD6 (1.00) ABHD6
SCHEMBL20983868 0.83 ABHD6 (0.71) ABHD6
SCHEMBL20983726 0.82 ABHD6 (1.00) ABHD6
SCHEMBL772680 0.82 ABHD6 (0.69) ABHD6
SCHEMBL20983734 0.82 ABHD6 (1.00) ABHD6
SCHEMBL20983749 0.81 ABHD6 (0.69) ABHD6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190152917-A1 ABHD6 AND DUAL ABHD6/MGL INHIBITORS AND THEIR USES MAKSCIENTIFIC, LLC 2019-05-23 — — US claimed
US-10662159-B2 ABHD6 and dual ABHD6/MGL inhibitors and their uses MAKSCIENTIFIC, LLC (US) 2020-05-26 — — US disclosed
US-20190152917-A1 ABHD6 AND DUAL ABHD6/MGL INHIBITORS AND THEIR USES MAKSCIENTIFIC, LLC 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10662159-B2 ABHD6 and dual ABHD6/MGL inhibitors and their uses ABHD6, FAAH, FAAH2 ABHD6 1/4885
US-20190152917-A1 ABHD6 AND DUAL ABHD6/MGL INHIBITORS AND THEIR USES ABHD6, FAAH, FAAH2 ABHD6 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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