SCHEMBL2098522

SCHEMBL2098522

CCCCc1ccc(NC)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.53
HPGD P15428 4/20 0.53
POLB P06746 1/20 0.53
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
CA2 P00918 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
CA1 P00915 1/20 0.50
ALDH1A1 P00352 3/20 0.49
LMNA P02545 2/20 0.49
HSD17B10 Q99714 2/20 0.48
FFAR1 O14842 1/20 0.47
FFAR4 Q5NUL3 1/20 0.47
ESR1 P03372 2/20 0.47
ADRA2A P08913 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2863755 0.98 PLK1 (0.52) PLK1HPGDPOLBNPC1RAB9A
SCHEMBL27496644 0.93 ESR1 (0.55) CA2ALDH1A1LMNAHSD17B10ESR1
SCHEMBL30468687 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL4083403 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL19513921 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL8963454 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL4089466 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL8963483 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL15766189 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A
SCHEMBL4093509 0.91 ESR1 (0.59) ALDH1A1LMNAHSD17B10ESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE FREISTAAT BAYERN LUDWIG MAXIMILIANS UNIV MUENCHEN (DE) 2025-12-11 US disclosed
US-11414436-B2 Non-coordinating anion type activators containing cation having large alkyl groups EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-08-16 US disclosed
EP-2968330-B1 COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS SCRIPPS RESEARCH INST (US) 2021-09-29 EP disclosed
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups EXXONMOBIL CHEMICAL PATENTS INC. 2019-10-31 US disclosed
CN-109678852-A 6- oxo hexahydropyrimidine derivative, preparation method and pharmacy application 南京中医药大学 2019-04-26 CN disclosed
WO-2018138591-A1 CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF PFIZER INC. (US) 2018-08-02 WO disclosed
WO-2017192811-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE BRISTOL-MYERS SQUIBB COMPANY (US) 2017-11-09 WO disclosed
EP-2509600-B1 THERAPEUTICALLY ACTIVE COMPOUNDS FOR USE IN THE TREATMENT OF CANCER CHARACTERIZED AS HAVING AN IDH MUTATION AGIOS PHARMACEUTICALS INC (US) 2017-08-02 EP disclosed
CN-103890056-B Carbon fiber-reinforced thermoplastic resin composition, molding material, prepreg, and methods for producing same TORAY INDUSTRIES 2015-07-22 CN disclosed
CN-102791750-B Ethylene-alpha-olefin copolymer and molded article SUMITOMO CHEMICAL CO.,LTD. (JP) 2014-10-29 CN disclosed
EP-0849292-B1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORP (JP) 2002-08-21 EP disclosed
US-6372681-B1 METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2002-04-16 US disclosed
CN-1306011-A Polyaddition catalyst component, polyaddition catalyst and method for preparing addition polymer SUMITOMO CHEMICAL CO (JP) 2001-08-01 CN disclosed
EP-1044997-A2 Aromatic aldehyde resins and their use as demulsifier Clariant GmbH (DE) 2000-10-18 EP disclosed
US-6110858-A AN OLEFIN POLYMERIZATION CATALYST CONSISTS OF A TRANSITION METAL COMPOUND, A MODIFIED CLAY COMPOUND CONTAINING CLAY MINERAL AND AN AMINE COMPOUND AND AN ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2000-08-29 US disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0849292-A1 Olefin polymerisation catalysts and processes for producing olefin polymers TOSOH CORPORATION (JP) 1998-06-24 EP disclosed
US-4436641-A ANTHRAQUINONE DYES RACON INCORPORATED (US) 1984-03-13 US disclosed
US-4369120-A ANTHRAQUINONE DYES RACON INCORPORATED (US) 1983-01-18 US disclosed
US-3981717-A ANILINO COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1976-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE CRY1, MKI67, IK PLK1 3320/4885HPGD 1757/4885POLB 2812/4885
US-11414436-B2 Non-coordinating anion type activators containing cation having large alkyl groups KCNK10, KCNK4, HCN4 PLK1 1885/4885HPGD 2481/4885POLB 3297/4885
US-20190330139-A1 Non-Coordinating Anion Type Activators Containing Cation Having Large Alkyl Groups KCNK10, KCNK4, HCN4 PLK1 1872/4885HPGD 2459/4885POLB 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.