Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | CES2 | O00748 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578308 | 0.95 | TDP1 (0.56) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL599761 | 0.89 | TDP1 (0.61) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL6120810 | 0.86 | TDP1 (0.48) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL5706065 | 0.81 | KMT2A (0.51) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL7105558 | 0.80 | TDP1 (0.54) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL14512285 | 0.80 | TDP1 (0.52) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL2853917 | 0.80 | TDP1 (0.52) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL27491745 | 0.80 | TDP1 (0.52) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL600051 | 0.80 | TDP1 (0.52) | TDP1L3MBTL1CES1CES2LMNA | |
| SCHEMBL2636176 | 0.80 | MAPT (0.47) | TDP1L3MBTL1CES1CES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111348996-B | 2-benzoyl malonate compound, and preparation method and application thereof | 江苏联化科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| WO-2020132792-A1 | 2-BENZOYL MALONATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏联化科技有限公司 | 2020-07-02 | — | — | WO | claimed |
| CN-111348996-A | 2-benzoyl malonate compound, preparation method and application thereof | 江苏联化科技有限公司 | 2020-06-30 | — | — | CN | claimed |
| CN-111348996-B | 2-benzoyl malonate compound, and preparation method and application thereof | 江苏联化科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| WO-2020132792-A1 | 2-BENZOYL MALONATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏联化科技有限公司 | 2020-07-02 | — | — | WO | disclosed |
| CN-111348996-A | 2-benzoyl malonate compound, preparation method and application thereof | 江苏联化科技有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-105431133-A | Colloidally stable dispersions based on modified galactomannans | LUBRIZOL ADVANCED MAT INC | 2016-03-23 | — | — | CN | disclosed |
| US-8372300-B2 | Additives for electrolyte solution and electrolyte solution | OTSUKA CHEMICAL CO., LTD. (JP) | 2013-02-12 | — | — | US | disclosed |
| EP-2037468-B1 | ADDITIVE FOR ELECTROLYTE SOLUTION AND ELECTROLYTE SOLUTION | OTSUKA CHEMICAL CO LTD (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120170172-A1 | ADDITIVES FOR ELECTROLYTE SOLUTION AND ELECTROLYTE SOLUTION | OKA AKINORI (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8163195-B2 | Additives for electrolyte solution and electrolyte solution | OTSUKA CHEMICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| US-20090309060-A1 | Additives for Electrolyte Solution and Electrolyte Solution | OTSUKA CHEMICAL CO., LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-0523956-B2 | Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1999-02-03 | — | — | EP | disclosed |
| EP-0523955-A2 | Water dispersible or water soluble copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1993-01-20 | — | — | EP | disclosed |
| EP-0523956-A2 | Fabric care composition comprising water soluble or water dispersible copolymer containing UV-absorbing monomer | UNILEVER PLC (GB) | 1993-01-20 | — | — | EP | disclosed |
| US-5134223-A | Fabric colorfastness | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-4847375-A | Antibacterial 1,8-bridged 4-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090309060-A1 | Additives for Electrolyte Solution and Electrolyte Solution | SLC9A1, SLC26A3, AQP1 | TDP1 2723/4885L3MBTL1 3586/4885CES1 890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.