Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987593 | 0.79 | EGLN1 (0.53) | CYP2C19ALDH1A1HPGDGAAMGAM | |
| SCHEMBL12017898 | 0.78 | CYP2D6 (0.41) | ALDH1A1GAACTSKCYP2D6CTSS | |
| SCHEMBL29037226 | 0.77 | MEN1 (0.46) | ALDH1A1GAACTSKCYP2D6CTSS | |
| SCHEMBL1455828 | 0.76 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL23354859 | 0.75 | MEN1 (0.46) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL29873577 | 0.75 | MEN1 (0.46) | CYP1A2CYP2C9CYP2C19HTTALDH1A1 | |
| SCHEMBL2113714 | 0.75 | CYP2D6 (0.39) | ALDH1A1GAACTSKCYP2D6CTSS | |
| SCHEMBL12884403 | 0.75 | CYP2D6 (0.42) | ALDH1A1GAACTSKCYP2D6CTSS | |
| SCHEMBL18556352 | 0.75 | ALDH1A1 (0.57) | ALDH1A1GAACTSKCYP2D6CTSS | |
| SCHEMBL27072723 | 0.75 | CYP2D6 (0.39) | ALDH1A1GAACTSKCYP2D6CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084796-B2 | Heterocyclic derivatives for the treatment of RSV | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20190135770-A1 | HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF RSV | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135770-A1 | HETEROCYCLIC DERIVATIVES FOR THE TREATMENT OF RSV | MAVS, HMGB3, NIPSNAP3A | CYP1A2 4038/4885CYP2C9 4704/4885CYP2C19 4394/4885 |
| US-11084796-B2 | Heterocyclic derivatives for the treatment of RSV | MAVS, HMGB3, NIPSNAP3A | CYP1A2 4038/4885CYP2C9 4704/4885CYP2C19 4394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.