Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 2/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL5488702 | 0.90 | ALOX15 (0.59) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| SCHEMBL29428422 | 0.85 | — | — | |
| SCHEMBL102738 | 0.85 | — | — | |
| Sulfuric Acid SCHEMBL28204624 | 0.84 | TDP1 (0.50) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL28282145 | 0.84 | TDP1 (0.50) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL826783 | 0.83 | TDP1 (0.94) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28219263 | 0.83 | TDP1 (0.94) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL3343913 | 0.83 | ALDH1A1 (0.79) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Sulfur Dioxide SCHEMBL28455461 | 0.81 | TDP1 (0.80) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29467723 | 0.80 | TDP1 (0.89) | ALOX15CYP3A4TDP1THRBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11517514-B2 | Resorcinol-free hair colouring compositions | BEAUTY & BUSINESS S.P.A. (IT) | 2022-12-06 | — | — | US | claimed |
| EP-4066812-A1 | RESORCINOL-FREE HAIR COLOURING COMPOSITIONS | Beauty & Business S.p.A. (IT) | 2022-10-05 | — | — | EP | claimed |
| US-20220304908-A1 | RESORCINOL-FREE HAIR COLOURING COMPOSITIONS | BEAUTY & BUSINESS S.P.A. (IT) | 2022-09-29 | — | — | US | claimed |
| EP-3634365-B1 | HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE | HENKEL AG & CO KGAA (DE) | 2022-08-10 | — | — | EP | claimed |
| EP-3496818-B1 | PROCESS FOR PREPARING HAIR DYE AGENTS HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES | HENKEL AG & CO KGAA (DE) | 2021-01-20 | — | — | EP | claimed |
| EP-3634365-A1 | HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE | Henkel AG & Co. KGaA (DE) | 2020-04-15 | — | — | EP | claimed |
| EP-1429715-B1 | HAIR COLOURING COMPOSITIONS | BOOTS CO PLC (GB) | 2010-11-24 | — | — | EP | claimed |
| US-7172632-B2 | Hair coloring compositions | THE BOOTS COMPANY, PLC (GB) | 2007-02-06 | — | — | US | claimed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | claimed |
| EP-1429715-A2 | HAIR COLOURING COMPOSITIONS | The Boots Company PLC (GB) | 2004-06-23 | — | — | EP | claimed |
| WO-2003015734-A2 | HAIR COLOURING COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2003-02-27 | — | — | WO | claimed |
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | HENKEL AG & CO. KGAA (DE) | 2026-05-12 | — | — | US | disclosed |
| US-12290584-B2 | Hair dyeing method using natural dyes and metal salt | HENKEL AG & CO. KGAA (DE) | 2025-05-06 | — | — | US | disclosed |
| EP-4496559-A1 | AGENT FOR OXIDATIVE DYEING OF KERATIN FIBRES, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | disclosed |
| EP-4496555-A1 | MEANS FOR OXIDATIVELY DYEING KERATIN FIBRES, CONTAINING AT LEAST ONE OXIDATION DYE PRECURSOR OF THE P-PHENYLENEDIAMINE TYPE, ISATIN AND AT LEAST ONE OXIDISING AGENT | Henkel AG & Co. KGaA (DE) | 2025-01-29 | — | — | EP | disclosed |
| US-5230710-A | SUBSTITUTED 2,6-DIAMINOTOLUENES, PROCESSES FOR THEIR PREPARATION AND COLORING AGENTS FOR KERATINIC FIBERS COMPRISING THESE COMPOUNDS | HANS SCHWARZKOPF GMBH (DE) | 1993-07-27 | — | — | US | disclosed |
| US-4196145-A | OXIDATION COLOR DYES | CLAIROL INCORPORATED (US) | 1980-04-01 | — | — | US | disclosed |
| US-4092102-A | HAIR DYES, OXIDATION DYES | CLAIROL INCORPORATED (US) | 1978-05-30 | — | — | US | disclosed |
| US-4054413-A | PREFORMED SOLUTION OF TRIACETATE OF A BENZENETRIOL, A P-PHENYLENEDIAMINE | CLAIROL INCORPORATED (US) | 1977-10-18 | — | — | US | disclosed |
| US-3981677-A | Oxidative hair dye compositions containing N-substituted o-phenylenediamines and method for their use | CLAIROL INCORPORATED (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | KRT18, ARSA, MKI67 | ALOX15 2308/4885CYP3A4 1878/4885TDP1 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.