SCHEMBL20988552

SCHEMBL20988552

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5c4ccc4c6ccccc6n(-c6cccc7ccccc67)c45)cc3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 3/20 0.39
KDM4E B2RXH2 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
PDE6D O43924 1/20 0.34
HDAC4 P56524 1/20 0.32
ALDH1A1 P00352 3/20 0.32
TDP1 Q9NUW8 2/20 0.32
GSR P00390 1/20 0.31
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
HPGD P15428 2/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
MAPK1 P28482 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12690893 0.97 ATM (0.35) ATMKDM4EL3MBTL1PDE6DALDH1A1
SCHEMBL22595551 0.93 KMT2A (0.36) ATMKDM4EL3MBTL1PDE6DALDH1A1
SCHEMBL21566447 0.93 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDE6DHDAC4
SCHEMBL23232219 0.93 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDE6DHDAC4
SCHEMBL22596126 0.92 KMT2A (0.36) ATMKDM4EL3MBTL1PDE6DHDAC4
SCHEMBL21365613 0.92 L3MBTL1 (0.43) ATMKDM4EL3MBTL1PDE6DHDAC4
SCHEMBL21365902 0.91 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDE6DHDAC4
SCHEMBL2741446 0.91 ALDH1A1 (0.33) ATMKDM4EL3MBTL1ALDH1A1TDP1
SCHEMBL20988529 0.90 ATM (0.39) ATMKDM4EL3MBTL1PDE6DALDH1A1
SCHEMBL19268701 0.90 ATM (0.45) ATMKDM4EL3MBTL1HDAC4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11183646-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-23 US disclosed
US-20190140193-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-05-09 US disclosed