SCHEMBL21566447

SCHEMBL21566447

c1ccc(-c2ccc(-n3c4ccccc4c4c3ccc3c5ccccc5n(-c5cccc6ccccc56)c34)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
PDE6D O43924 1/20 0.39
HDAC4 P56524 1/20 0.37
TDP1 Q9NUW8 1/20 0.35
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
ALDH1A1 P00352 2/20 0.33
KMT2A Q03164 2/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HTR6 P50406 1/20 0.32
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23232219 1.00 L3MBTL1 (0.42) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL23233689 0.96 PDE6D (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL21566444 0.96 PDE6D (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL23008278 0.95 KDM4E (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL23008381 0.95 KDM4E (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL19769609 0.95 KDM4E (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL19653602 0.94 L3MBTL1 (0.41) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL17019465 0.93 KDM4E (0.44) L3MBTL1KDM4EATMTDP1CNR1
SCHEMBL20988552 0.93 ATM (0.39) L3MBTL1KDM4EATMPDE6DHDAC4
SCHEMBL19769664 0.93 KDM4E (0.42) L3MBTL1KDM4EATMPDE6DHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210111350-A1 PHOSPHORESCENT HOST COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-04-15 US disclosed
US-20190348612-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2019-11-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190348612-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE, AND DISPLAY DEVICE OCIAD2, OR10J3, OCIAD1 L3MBTL1 4726/4885KDM4E 3780/4885ATM 4007/4885
US-20210111350-A1 PHOSPHORESCENT HOST COMPOSITION, ORGANIC OPTOELECTRONIC DIODE, AND DISPLAY DEVICE ORC3, CRY1, OSTC L3MBTL1 4140/4885KDM4E 4468/4885ATM 4137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.