Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29350612 | 0.90 | ACE (0.58) | OPRD1OPRM1OPRK1 | |
| SCHEMBL11044131 | 0.88 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL11043731 | 0.88 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL11045742 | 0.88 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL11042205 | 0.88 | OPRK1 (0.53) | OPRK1 | |
| SCHEMBL24520152 | 0.88 | BACE1 (0.58) | — | |
| SCHEMBL31062497 | 0.88 | OPRD1 (0.62) | OPRD1 | |
| SCHEMBL10596196 | 0.87 | OPRD1 (0.64) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9513983 | 0.87 | SLC7A5 (0.51) | OPRD1OPRM1OPRK1 | |
| SCHEMBL9419218 | 0.87 | SLC7A5 (0.51) | OPRD1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135865-A1 | AGONIST AGENTS OF CD47 INDUCING PROGRAMMED CELL DEATH AND THEIR USE IN THE TREATMENTS OF DISEASES ASSOCIATED WITH DEFECTS IN PROGRAMMED CELL DEATH | SORBONNE UNIVERSITE (FR) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135865-A1 | AGONIST AGENTS OF CD47 INDUCING PROGRAMMED CELL DEATH AND THEIR USE IN THE TREATMENTS OF DISEASES ASSOCIATED WITH DEFECTS IN PROGRAMMED CELL DEATH | CD47, BID, CD274 | OPRD1 3381/4885OPRM1 3781/4885OPRK1 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.