SCHEMBL9419218

SCHEMBL9419218

CC(C)[C@H](NC(=O)[C@H](N)Cc1ccc(O)cc1)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.51
YARS1 P54577 2/20 0.50
OPRD1 P41143 8/20 0.49
OPRM1 P35372 4/20 0.49
OPRK1 P41145 1/20 0.49
TAAR1 Q96RJ0 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513983 1.00 SLC7A5 (0.51) SLC7A5YARS1OPRD1OPRM1OPRK1
SCHEMBL30863567 0.91 OPRD1 (0.51) OPRD1OPRM1OPRK1
SCHEMBL29462561 0.89 SLC7A5 (0.59) SLC7A5YARS1OPRD1OPRM1OPRK1
SCHEMBL29531284 0.89 SLC7A5 (0.59) SLC7A5YARS1OPRD1OPRM1OPRK1
Hydrochloric Acid SCHEMBL30698094 0.87 SLC7A5 (0.58) SLC7A5YARS1OPRD1OPRM1OPRK1
SCHEMBL20990366 0.87 OPRD1 (0.58) OPRD1OPRM1OPRK1
SCHEMBL31276527 0.86 SLC7A5 (0.56) SLC7A5YARS1OPRD1OPRM1OPRK1
SCHEMBL5686804 0.84 OPRD1 (0.54) OPRD1OPRM1OPRK1
SCHEMBL22644029 0.84 OPRD1 (0.55) SLC7A5YARS1OPRD1OPRM1OPRK1
SCHEMBL31265324 0.84 OPRD1 (0.56) SLC7A5YARS1OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250099554-A1 COMPOSITIONS AND METHODS OF FAS INHIBITION ONL THERAPEUTICS INC (US) 2025-03-27 US disclosed
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL THERAPEUTICS, INC. 2024-06-20 US disclosed
EP-4370208-A2 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL Therapeutics, Inc. (US) 2024-05-22 EP disclosed
US-20240156898-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL THERAPEUTICS, INC. 2024-05-16 US disclosed
EP-4355349-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL Therapeutics, Inc. (US) 2024-04-24 EP disclosed
WO-2023287794-A2 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL THERAPEUTICS, INC. (US) 2023-01-19 WO disclosed
WO-2022266127-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES ONL THERAPEUTICS, INC. (US) 2022-12-22 WO disclosed
US-5354675-A Amidation of glycine SHISEIDO COMPANY LTD. (JP) 1994-10-11 US disclosed
EP-0447547-B1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO CO LTD (JP) 1994-07-27 EP disclosed
EP-0447547-A1 C-TERMINUS AMIDATION ENZYME COMPOSITION, PROCESS FOR ITS PREPARATION AND ITS USE SHISEIDO COMPANY LIMITED (JP) 1991-09-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS PDE6C, UACA, EYA3 SLC7A5 570/4885YARS1 3328/4885OPRD1 4615/4885
US-20240156898-A1 METHODS AND COMPOSITIONS FOR TREATING OCULAR DISORDERS AND DISEASES UACA, ASAH2, NFKBIA SLC7A5 4763/4885YARS1 3155/4885OPRD1 4411/4885
US-20250099554-A1 COMPOSITIONS AND METHODS OF FAS INHIBITION CFB, BAX, FASN SLC7A5 4772/4885YARS1 3383/4885OPRD1 4243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.