Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2102483 | 0.89 | ABCB11 (0.57) | CNR2ABCB11GSTO1TP53PKM | |
| SCHEMBL2100338 | 0.84 | PTGDR2 (0.50) | CNR2GSTO1TP53PKMRAB9A | |
| SCHEMBL2099475 | 0.84 | ABCB11 (0.46) | CNR2ABCB11GSTO1TP53PKM | |
| SCHEMBL2099477 | 0.82 | CNR2 (0.46) | CNR2GSTO1TP53PKMRAB9A | |
| SCHEMBL3838582 | 0.82 | CNR2 (0.47) | CNR2GSTO1TP53PKMRAB9A | |
| SCHEMBL2101692 | 0.78 | CNR2 (0.49) | CNR2GSTO1TP53PKMRAB9A | |
| SCHEMBL2101099 | 0.77 | MC2R (0.41) | ABCB11RAB9APTGDR2 | |
| SCHEMBL2102466 | 0.74 | ABCB11 (0.62) | ABCB11PTGDR2 | |
| SCHEMBL2099206 | 0.74 | ABCB11 (0.64) | ABCB11PTGDR2 | |
| SCHEMBL1753809 | 0.72 | MEN1 (0.56) | PKMGAAALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |