Benzoic Acid

Benzoic Acid

SCHEMBL2099291

C=C(C)C(=O)OCC(CC)(CO)CO.O=C(O)c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D

The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
POLB P06746 2/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
ELANE P08246 1/20 0.40
TSHR P16473 2/20 0.38
DAO P14920 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
LMNA P02545 1/20 0.36
CYP2D6 P10635 2/20 0.35
HTR1A P08908 1/20 0.35
SCN1A P35498 1/20 0.35
SLC6A3 Q01959 1/20 0.35
SCN5A Q14524 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL644017 0.88 MAPK1 (0.56) TDP1POLBAPEX1HTTMAPK1
SCHEMBL11804340 0.85 MAPK1 (0.46) TDP1POLBMAPK1HIF1AALDH1A1
SCHEMBL9172153 0.85 MAPK1 (0.63) TDP1POLBAPEX1HTTMAPK1
SCHEMBL30451 0.84 THRB (0.44) TDP1POLBAPEX1HTTMAPK1
SCHEMBL2140682 0.83 MAPK1 (0.61) TDP1POLBAPEX1HTTMAPK1
SCHEMBL3410019 0.83 MAPK1 (0.61) TDP1POLBAPEX1HTTMAPK1
Benzoic Acid SCHEMBL28085428 0.83 DAO (0.45) TDP1POLBAPEX1HTTMAPK1
Benzoic Acid SCHEMBL4117667 0.83 DAO (0.45) TDP1POLBAPEX1HTTMAPK1
SCHEMBL5446418 0.82 THRB (0.43) MAPK1HIF1AALDH1A1TSHRTHRB
SCHEMBL2637971 0.82 THRB (0.43) MAPK1HIF1AALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2602811-B1 PHOTOCURABLE COMPOSITION AND METHOD FOR PRODUCING MOLDED BODY HAVING SURFACE THAT IS PROVIDED WITH FINE PATTERN ASAHI GLASS CO LTD (JP) 2017-11-08 EP disclosed
US-20150116820-A1 FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
EP-2796904-A1 FILM MIRROR FOR SOLAR LIGHT REFLECTION, AND REFLECTIVE DEVICE FOR SOLAR POWER GENERATION Konica Minolta, Inc. (JP) 2014-10-29 EP disclosed
EP-2602811-A1 PHOTOCURABLE COMPOSITION AND METHOD FOR PRODUCING MOLDED BODY HAVING SURFACE THAT IS PROVIDED WITH FINE PATTERN Asahi Glass Company, Limited (JP) 2013-06-12 EP disclosed
US-20120175821-A1 PHOTOCURABLE COMPOSITION AND METHOD FOR PRODUCING MOLDED PRODUCT WITH FINE PATTERN ASAHI GLASS COMPANY, LIMITED (JP) 2012-07-12 US disclosed
EP-2159236-B1 PHOTOCURABLE COMPOSITION AND PROCESS FOR PRODUCING MOLDED OBJECT HAVING FINE PATTERN IN SURFACE ASAHI GLASS CO LTD (JP) 2012-05-02 EP disclosed
US-8163813-B2 Photocurable composition and method for producing molded product with fine pattern ASAHI GLASS COMPANY, LIMITED (JP) 2012-04-24 US disclosed
EP-2159236-A1 PHOTOCURABLE COMPOSITION AND PROCESS FOR PRODUCING MOLDED OBJECT HAVING FINE PATTERN IN SURFACE Asahi Glass Company, Limited (JP) 2010-03-03 EP disclosed
US-20100038831-A1 PHOTOCURABLE COMPOSITION AND METHOD FOR PRODUCING MOLDED PRODUCT WITH FINE PATTERN ASAHI GLASS COMPANY, LIMITED (JP) 2010-02-18 US disclosed