Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547607 | 0.85 | MAPK1 (0.49) | MAPK1HIF1ATDP1ALDH1A1MAPT | |
| Benzoic Acid SCHEMBL2099291 | 0.85 | TDP1 (0.45) | MAPK1HIF1ATDP1ATMALDH1A1 | |
| SCHEMBL505769 | 0.81 | MAPK1 (0.71) | MAPK1HIF1ATDP1ALDH1A1LMNA | |
| SCHEMBL644017 | 0.81 | MAPK1 (0.56) | MAPK1HIF1ATDP1ALDH1A1MAPT | |
| Methacrylic Acid SCHEMBL36396 | 0.80 | MAPK1 (0.59) | MAPK1HIF1ATDP1ALDH1A1MAPT | |
| SCHEMBL4908891 | 0.80 | TDP1 (0.54) | MAPK1HIF1ATDP1ATMALDH1A1 | |
| SCHEMBL11804358 | 0.80 | ATM (0.40) | MAPK1HIF1ATDP1ATMALDH1A1 | |
| SCHEMBL8858245 | 0.80 | TDP1 (0.54) | MAPK1HIF1ATDP1ATMALDH1A1 | |
| SCHEMBL11804351 | 0.79 | TDP1 (0.43) | MAPK1HIF1ATDP1ATMALDH1A1 | |
| SCHEMBL11436193 | 0.78 | MAPK1 (0.71) | MAPK1HIF1ATDP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935342-A | POLYMERIZATION WITH AN UNSATURATED SILYL MONOMER | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-27 | — | — | US | disclosed |