Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23593943 | 0.77 | AKR1C1 (0.70) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL6689798 | 0.77 | AKR1C1 (0.70) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL2836206 | 0.77 | AKR1C1 (0.70) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL16102105 | 0.77 | PDE10A (0.40) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL3652893 | 0.76 | GCK (0.48) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL21682467 | 0.75 | NPC1 (0.40) | AKR1C1CYP2C19TDP1POLBMAPT | |
| SCHEMBL5014082 | 0.74 | NPC1 (0.38) | AKR1C1MAPTNPC1RAB9ACDK5 | |
| SCHEMBL16180696 | 0.73 | CYP11B2 (0.61) | AKR1C1CYP2C19MAPTCYP3A4KMT2A | |
| SCHEMBL5257618 | 0.73 | KMT2A (0.54) | KMT2A | |
| SCHEMBL5257623 | 0.73 | KMT2A (0.54) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4643954-A2 | NOVEL HETEROCYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2025-11-05 | — | — | EP | disclosed |
| US-12227498-B2 | Heterocyclic amine derivative and pharmaceutical composition comprising same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2025-02-18 | — | — | US | disclosed |
| CN-115151537-B | Process for preparing heterocyclic amine derivatives | 株式会社大熊制药 | 2024-09-06 | — | — | CN | disclosed |
| CN-112638910-B | New heterocyclic amine derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2024-06-11 | — | — | CN | disclosed |
| EP-3481831-B1 | 4-AMINOPYRAZOLO[3,4-D]PYRIMIDINYLAZABICYCLO DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO LTD (KR) | 2023-09-06 | — | — | EP | disclosed |
| US-20230094404-A1 | METHOD FOR PREPARATION OF HETEROCYCLICAMINE DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2023-03-30 | — | — | US | disclosed |
| EP-4112617-A1 | METHOD FOR PREPARATION OF HETEROCYCLICAMINE DERIVATIVES | Daewoong Pharmaceutical Co., Ltd. (KR) | 2023-01-04 | — | — | EP | disclosed |
| CN-115151537-A | Process for preparing heterocyclic amine derivatives | 株式会社大熊制药 | 2022-10-04 | — | — | CN | disclosed |
| CN-111212833-B | Phenylpyridine derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2022-09-06 | — | — | CN | disclosed |
| EP-3696176-B1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAE WOONG PHARMA (KR) | 2022-05-04 | — | — | EP | disclosed |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2021-10-19 | — | — | US | disclosed |
| EP-3845530-A1 | NOVEL HETEROCYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2021-07-07 | — | — | EP | disclosed |
| CN-109153680-B | 4-aminopyrazolo [3,4-d ] pyrimidinylazabicyclo derivatives and pharmaceutical compositions containing the same | 株式会社大熊制药 | 2021-04-23 | — | — | CN | disclosed |
| CN-112638910-A | Novel heterocyclic amine derivatives and pharmaceutical compositions comprising the same | 株式会社大熊制药 | 2021-04-09 | — | — | CN | disclosed |
| EP-3696176-A1 | NOVEL PHENYLPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-08-19 | — | — | EP | disclosed |
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2020-07-16 | — | — | US | disclosed |
| CN-111212833-A | Novel phenylpyridine derivative and pharmaceutical composition comprising same | 株式会社大熊制药 | 2020-05-29 | — | — | CN | disclosed |
| CN-110914266-A | Novel 1H-pyrazolopyridine derivative and pharmaceutical composition comprising the same | 株式会社大熊制药 | 2020-03-24 | — | — | CN | disclosed |
| US-10399988-B2 | 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical composition comprising the same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2019-09-03 | — | — | US | disclosed |
| US-20190161488-A1 | Novel 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo Derivatives and Pharmaceutical Composition Comprising the Same | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10399988-B2 | 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo derivatives and pharmaceutical composition comprising the same | ITK, BTK, TYK2 | AKR1C1 3823/4885CYP2C19 1754/4885TDP1 916/4885 |
| US-20230094404-A1 | METHOD FOR PREPARATION OF HETEROCYCLICAMINE DERIVATIVES | HNMT, MAOB, PNMT | AKR1C1 3261/4885CYP2C19 120/4885TDP1 429/4885 |
| US-20200223821-A1 | Novel Phenylpyridine Derivative and Pharmaceutical Composition Comprising the Same | PDCD1, PDCD5, PDCD11 | AKR1C1 1562/4885CYP2C19 976/4885TDP1 33/4885 |
| US-20190161488-A1 | Novel 4-aminopyrazolo[3,4-d]pyrimidinylazabicyclo Derivatives and Pharmaceutical Composition Comprising the Same | BTK, ITK, TYK2 | AKR1C1 4140/4885CYP2C19 2171/4885TDP1 866/4885 |
| US-12227498-B2 | Heterocyclic amine derivative and pharmaceutical composition comprising same | H1-5, SSB, H1-2 | AKR1C1 564/4885CYP2C19 415/4885TDP1 444/4885 |
| US-11149019-B2 | Phenylpyridine derivative and pharmaceutical composition comprising the same | DPYD, PDCD5, PDCD1 | AKR1C1 1515/4885CYP2C19 599/4885TDP1 42/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.