SCHEMBL21012174

SCHEMBL21012174

OBc1nc(-c2ccccc2)nc(-c2ccccc2)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.54
▸ ADORA2A P29274 3/20 0.48
▸ ADORA1 P30542 3/20 0.48
▸ ADORA3 P0DMS8 2/20 0.48
▸ ADORA2B P29275 2/20 0.48
▸ POLB P06746 2/20 0.48
▸ NPC1 O15118 3/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ MEN1 O00255 5/20 0.45
▸ KMT2A Q03164 5/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ MAPT P10636 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ NTSR1 P30989 1/20 0.45
▸ TSHR P16473 2/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ HTT P42858 1/20 0.43
▸ NR1H2 P55055 2/20 0.41
▸ NR1H3 Q13133 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18662233 0.87 L3MBTL1 (0.61) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL21975473 0.82 L3MBTL1 (0.50) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL371042 0.82 L3MBTL1 (0.74) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL18212420 0.79 L3MBTL1 (0.70) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL75848 0.79 L3MBTL1 (0.70) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL6112014 0.79 L3MBTL1 (0.70) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL17720978 0.79 L3MBTL1 (0.70) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL22248248 0.77 L3MBTL1 (0.45) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL28938233 0.77 ADORA2A (0.50) L3MBTL1ADORA2AADORA1ADORA3ADORA2B
SCHEMBL23608941 0.76 L3MBTL1 (0.67) L3MBTL1ADORA2AADORA1ADORA3ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-27 — — US disclosed
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-08-19 — — US disclosed
US-11024811-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-06-01 — — US disclosed
EP-3197982-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-05-06 — — EP disclosed
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-08-22 — — US disclosed
US-10297762-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190259957-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM L3MBTL1 2467/4885ADORA2A 4012/4885ADORA1 4079/4885
US-20210257554-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM L3MBTL1 2467/4885ADORA2A 4012/4885ADORA1 4079/4885
US-11024811-B2 Organic electroluminescent materials and devices SOD1, PIEZO1, L1CAM L3MBTL1 2467/4885ADORA2A 4012/4885ADORA1 4079/4885
US-20230130110-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, PIEZO1, L1CAM L3MBTL1 2467/4885ADORA2A 4012/4885ADORA1 4079/4885
US-10297762-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OR10J3 L3MBTL1 2272/4885ADORA2A 4607/4885ADORA1 4447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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