Fenspiride

Fenspiride

SCHEMBL21016

O=C1NCC2(CCN(CCc3ccccc3)CC2)O1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 1.00
CHRM2 P08172 1/20 1.00
ADRA2A P08913 1/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00
DRD1 P21728 1/20 1.00
MAPT P10636 1/20 0.97
KMT2A Q03164 1/20 0.97
SIGMAR1 Q99720 15/20 0.60
OPRM1 P35372 10/20 0.60
DRD2 P14416 4/20 0.57
HTR2A P28223 1/20 0.56
KCNH2 Q12809 4/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenspiride SCHEMBL9223216 0.99 LMNA (0.97) LMNACHRM2ADRA2ACYP2D6TSHR
Fenspiride SCHEMBL613462 0.99 MAPT (1.00) LMNACHRM2ADRA2ACYP2D6TSHR
Fenspiride SCHEMBL17006239 0.99 LMNA (0.97) LMNACHRM2ADRA2ACYP2D6TSHR
SCHEMBL9068521 0.86 LMNA (0.75) LMNACHRM2ADRA2ACYP2D6TSHR
SCHEMBL2604320 0.86 TSHR (0.75) LMNACHRM2ADRA2ACYP2D6TSHR
SCHEMBL11285193 0.83 LMNA (0.70) LMNACHRM2ADRA2ACYP2D6TSHR
Hydrochloric Acid SCHEMBL11284963 0.82 MAPT (0.71) LMNACHRM2ADRA2ACYP2D6TSHR
SCHEMBL17317198 0.82 LMNA (0.69) LMNACHRM2ADRA2ACYP2D6TSHR
Fenspiride SCHEMBL6671915 0.82 LMNA (0.67) LMNACHRM2ADRA2ACYP2D6TSHR
SCHEMBL17101331 0.81 TSHR (0.68) LMNACHRM2ADRA2ACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 35408 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026100654-A1 NUCLEIC ACID INTRODUCTION AID, NUCLEIC ACID INTRODUCTION AGENT, AND NUCLEIC ACID INTRODUCTION METHOD 株式会社インファーマシア 2026-05-15 WO claimed
US-20250319110-A1 SURFACE CALR CHEMICAL INDUCERS ZON LEONARD (US) 2025-10-16 US claimed
US-20250186415-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS FIFTH THIRD BANK, NATIONAL ASSOCIATION, AS AGENT 2025-06-12 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
EP-4540374-A1 SURFACE CALR CHEMICAL INDUCERS The Children's Medical Center Corporation (US) 2025-04-23 EP claimed
EP-4489858-A1 EXTENDED-RELEASE PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE CONDITIONS Harrow IP, LLC (US) 2025-01-15 EP claimed
EP-3713402-B1 FISH FARM WITH A ROOF COVER AND A FLOAT RING UNITECH OFFSHORE AS (NO) 2024-07-17 EP claimed
EP-3799895-B1 OPEN-CAVITY, REDUCED-PRESSURE TREATMENT DEVICES AND SYSTEMS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-17 EP claimed
EP-3947897-B1 HIERARCHICAL PRESSURE MANAGEMENT FOR MANAGED PRESSURE DRILLING OPERATIONS SAFEKICK AMERICAS LLC (US) 2024-07-17 EP claimed
EP-3218091-B1 FILTER ELEMENT WITH PROTRUSIONS DONALDSON CO INC (US) 2024-07-17 EP claimed
EP-0030353-A1 Process and apparatus for manufacturing disposable cannulae SORTIMAT Creuz & Co. GmbH (DE) 1981-06-17 EP claimed
EP-0029600-A1 Process for the separation of fluids by permeation Carl Still GmbH & Co. KG (DE) 1981-06-03 EP claimed
EP-0028347-A1 Transportable device for the receipt of substances to be shielded from the surroundings Reederei und Spedition "Braunkohle" GmbH. (DE) 1981-05-13 EP claimed
EP-0025562-A1 Piston-displacement pump, in particular metering pump Franz Klaus Union Armaturen Pumpen GmbH & Co. (DE) 1981-03-25 EP claimed
EP-0023548-A1 Multipart filter housing for the incorporation of several cartridge-shaped filter elements Sartorius GmbH. (DE) 1981-02-11 EP claimed
EP-0015550-A1 Method and device for determining the viscoelastic properties of fluids Fresenius AG (DE) 1980-09-17 EP claimed
EP-0011228-A1 Process for the removal of undesirable gaseous components from hot exhaust gases Linde Aktiengesellschaft (DE) 1980-05-28 EP claimed
EP-0010571-A1 Process and apparatus for carrying out (bio)chemical reactions and unit operations in fluid systems Blenke, Heinz, Prof. Dr.-Ing. (DE) 1980-05-14 EP claimed
EP-0008725-A1 Method and apparatus for determining the oxygen content in a reactor containing a mixture of fluids Firma Edmund Bühler (DE) 1980-03-19 EP claimed
EP-0006188-A1 Process of making a torus-shaped hollow body from mouldable and hardenable material METZELER KAUTSCHUK GMBH (DE) 1980-01-09 EP claimed