Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.51 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243310 | 0.83 | CHRNA10 (0.56) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL31753332 | 0.82 | HRH3 (0.48) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL28601340 | 0.82 | HRH3 (0.43) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL21888452 | 0.80 | HRH3 (0.44) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL19570981 | 0.79 | HRH3 (0.55) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL20046913 | 0.77 | HRH3 (0.43) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL19571344 | 0.77 | HRH3 (0.44) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL7374751 | 0.76 | KDM4E (0.52) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL31720517 | 0.76 | KDM4E (0.52) | CHRNA10CHRNA9HRH3KDM4ETP53 | |
| SCHEMBL23261764 | 0.75 | HRH3 (0.51) | CHRNA10CHRNA9HRH3KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190152947-A1 | PIPERIDINES AS MENIN INHIBITORS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152947-A1 | PIPERIDINES AS MENIN INHIBITORS | MEN1, GDI2, GNAQ | CHRNA10 2084/4885CHRNA9 2491/4885HRH3 307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.