Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.40 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020102 | 0.82 | CHRNA10 (0.51) | HRH3HTR7TMEM97CHRNA10CHRNA9 | |
| SCHEMBL29059217 | 0.81 | GHSR (0.38) | MEN1 | |
| SCHEMBL28731199 | 0.81 | LMNA (0.46) | HTR7TMEM97MEN1KDM4E | |
| SCHEMBL29090649 | 0.81 | GPR119 (0.47) | HTR7KDM4EITGAL | |
| SCHEMBL19571344 | 0.79 | HRH3 (0.44) | HRH3HTR7TMEM97CHRNA10CHRNA9 | |
| SCHEMBL28593067 | 0.78 | MEN1 (0.41) | MEN1 | |
| SCHEMBL28601342 | 0.76 | HRH3 (0.44) | HRH3HTR7TMEM97CHRNA10CHRNA9 | |
| SCHEMBL31753332 | 0.72 | HRH3 (0.48) | HRH3CHRNA10CHRNA9MEN1KDM4E | |
| SCHEMBL31411802 | 0.70 | CCKAR (0.34) | — | |
| SCHEMBL19570981 | 0.70 | HRH3 (0.55) | HRH3HTR7TMEM97CHRNA10CHRNA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166059-A | Small molecule MENIN inhibitors | 密歇根大学董事会 | 2021-07-23 | — | — | CN | disclosed |