Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021202 | 0.90 | KMT2A (0.39) | MAPK14HTTMEN1ALDH1A1RECQL | |
| SCHEMBL21020555 | 0.86 | HTT (0.34) | HTTMEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL21021225 | 0.81 | HTT (0.38) | MAPK14HTTMEN1ALDH1A1RECQL | |
| SCHEMBL21020626 | 0.78 | MAPK14 (0.37) | MAPK14HTTMEN1ALDH1A1RECQL | |
| SCHEMBL21021085 | 0.78 | PTGS1 (0.31) | — | |
| SCHEMBL21021207 | 0.77 | MEN1 (0.37) | MAPK14HTTMEN1ALDH1A1RECQL | |
| SCHEMBL21021307 | 0.75 | MEN1 (0.42) | HTTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL21020810 | 0.74 | LMNA (0.36) | HTTMEN1KMT2ALMNAHPGD | |
| SCHEMBL21022136 | 0.74 | ALDH1A1 (0.31) | MEN1ALDH1A1RECQLKMT2A | |
| SCHEMBL21022180 | 0.74 | NPC1 (0.33) | MEN1ALDH1A1RECQLKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |