SCHEMBL15317985

SCHEMBL15317985

CNc1ccc(-c2ccc(NC)cc2C)c(C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
PDK2 Q15119 1/20 0.38
TSHR P16473 1/20 0.38
CYP17A1 P05093 2/20 0.37
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
G6PD P11413 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
EGFR P00533 2/20 0.35
APP P05067 1/20 0.34
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34
ALDH1A1 P00352 2/20 0.33
RECQL P46063 2/20 0.33
HSD17B10 Q99714 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4180341 0.88 KDM4E (0.37) KDM4EPDK2TSHRCYP17A1ESR1
SCHEMBL26739579 0.83 ESR2 (0.55) KDM4EPDK2TSHRCYP17A1ESR2
SCHEMBL29606739 0.81 POLB (0.50) GAAKMT2AL3MBTL1LMNAPOLB
SCHEMBL2092210 0.81 POLB (0.50) GAAKMT2AL3MBTL1LMNAPOLB
SCHEMBL27343853 0.80 CYP1A2 (0.44) PDK2CYP17A1MEN1KMT2AEGFR
Hydrochloric Acid SCHEMBL2867268 0.79 POLB (0.48) GAAKMT2AL3MBTL1LMNAPOLB
SCHEMBL21021276 0.78 LMNA (0.37) TSHRAPPLMNAALDH1A1CYP3A4
SCHEMBL17178216 0.78 DRD1 (0.42) KDM4ETSHRGAAL3MBTL1EGFR
SCHEMBL8739061 0.77 ESR1 (0.41) TSHRESR1MEN1GAAG6PD
SCHEMBL19339697 0.77 KDM4E (0.43) KDM4ECYP17A1ESR1ESR2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8936840-B2 Retardation film, polarizing plate, liquid crystal display device, and compound Konica Minolta, Inc. (JP) 2015-01-20 US disclosed
US-8936840-B2 Retardation film, polarizing plate, liquid crystal display device, and compound Konica Minolta, Inc. (JP) 2015-01-20 US disclosed
US-8858767-B2 Polyamic acid and electrode for detecting hydrogen peroxide CHANG GUNG UNIVERSITY (TW) 2014-10-14 US disclosed
US-20130270112-A1 POLYAMIC ACID AND ELECTRODE FOR DETECTING HYDROGEN PEROXIDE Chang Gun University (TW) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130270112-A1 POLYAMIC ACID AND ELECTRODE FOR DETECTING HYDROGEN PEROXIDE HAO2, MPO, GPX4 KDM4E 3340/4885PDK2 542/4885TSHR 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.