Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020827 | 0.78 | MAOA (0.40) | ALDH1A1TDP1THRBHPGDMAPT | |
| SCHEMBL20076787 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL17850800 | 0.76 | ALDH1A1 (0.58) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL9073257 | 0.75 | CYP3A4 (0.50) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL197716 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL22819943 | 0.73 | NISCH (0.41) | ALDH1A1TDP1TP53THRBGAA | |
| SCHEMBL278053 | 0.73 | NISCH (0.41) | ALDH1A1TDP1TP53THRBGAA | |
| SCHEMBL21021611 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 | |
| SCHEMBL19857179 | 0.72 | PDE4A (0.46) | ALDH1A1TDP1CYP3A4SMN1; SMN2HPGD | |
| SCHEMBL20076595 | 0.71 | BRD4 (0.40) | ALDH1A1TDP1CYP3A4SMN1; SMN2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |