Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020813 | 0.76 | ALKBH3 (0.36) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL21022263 | 0.75 | TDP1 (0.39) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL20076748 | 0.74 | NFE2L2 (0.33) | ALKBH3 | |
| SCHEMBL22232130 | 0.73 | TDP1 (0.34) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL21021622 | 0.71 | ALDH1A1 (0.52) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL21021561 | 0.71 | ALDH1A1 (0.34) | TDP1ALOX15CYP3A4TP53THRB | |
| SCHEMBL21021863 | 0.69 | PTGES (0.43) | TP53SMN1; SMN2ALDH1A1ALKBH3RAPGEF4 | |
| SCHEMBL21021598 | 0.69 | ALDH1A1 (0.41) | ALDH1A1ALKBH3 | |
| SCHEMBL10343150 | 0.69 | PLA2G7 (0.47) | TDP1CYP3A4TP53ALDH1A1ALKBH3 | |
| SCHEMBL15340971 | 0.68 | CYP3A4 (0.48) | TDP1ALOX15CYP3A4TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |