Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20076794 | 0.86 | CYP2C9 (0.30) | CYP2C9CYP2C19 | |
| SCHEMBL20076742 | 0.81 | MEN1 (0.31) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL20076442 | 0.81 | MEN1 (0.38) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL21022007 | 0.81 | MEN1 (0.30) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL21022257 | 0.80 | NPC1 (0.31) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21021915 | 0.79 | MEN1 (0.42) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL20076386 | 0.78 | SLC9A1 (0.39) | — | |
| SCHEMBL21021560 | 0.78 | SMN1; SMN2 (0.37) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL20076565 | 0.75 | — | — | |
| SCHEMBL21020806 | 0.74 | TP53 (0.30) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |