Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 3/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021705 | 0.87 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1CHAT | |
| SCHEMBL11372722 | 0.83 | MAPT (0.41) | ALOX5PTGS1PTGS2ALDH1A1LMNA | |
| SCHEMBL21021183 | 0.81 | CHAT (0.61) | ALOX5PTGS1PTGS2TUBB1CHAT | |
| SCHEMBL21021699 | 0.81 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1DHFR | |
| SCHEMBL21021566 | 0.78 | ALOX5 (0.49) | ALOX5PTGS1PTGS2TUBB1CHAT | |
| SCHEMBL21022141 | 0.77 | ALOX5 (0.45) | ALOX5PTGS1PTGS2TUBB1DHFR | |
| SCHEMBL21021173 | 0.77 | CHAT (0.47) | ALOX5PTGS1PTGS2TUBB1CHAT | |
| SCHEMBL20076693 | 0.75 | ALOX5 (0.50) | ALOX5PTGS1PTGS2TUBB1CHAT | |
| SCHEMBL2439383 | 0.74 | ALDH1A1 (0.50) | ALDH1A1BACE1TTRKDM4EMAPT | |
| SCHEMBL21021035 | 0.74 | ALOX5 (0.53) | ALOX5PTGS1PTGS2TUBB1CHAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |