Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14989348 | 0.80 | PDE3B (0.42) | CYP3A4TSHRMAPK14PDE10AALDH1A1 | |
| SCHEMBL21021238 | 0.79 | PLA2G7 (0.62) | PLA2G7CYP3A4TSHRHSD11B1PDE10A | |
| SCHEMBL18430945 | 0.77 | PLA2G7 (0.75) | PLA2G7CYP3A4TSHRBRD4BRDT | |
| SCHEMBL14039912 | 0.77 | PDE3B (0.44) | PDE10ATLR8GPBAR1ESR1CA1 | |
| SCHEMBL2807338 | 0.77 | CYP3A4 (0.65) | PLA2G7CYP3A4TSHRALDH1A1CASP1 | |
| SCHEMBL21020966 | 0.76 | CYP3A4 (0.37) | PLA2G7CYP3A4TSHRDPP4ALDH1A1 | |
| SCHEMBL27186003 | 0.73 | CYP3A4 (0.61) | PLA2G7CYP3A4TSHRALDH1A1CASP1 | |
| SCHEMBL31661394 | 0.73 | CYP3A4 (0.61) | PLA2G7CYP3A4TSHRALDH1A1CASP1 | |
| SCHEMBL600882 | 0.72 | — | — | |
| SCHEMBL16280579 | 0.72 | ALDH1A1 (0.65) | PLA2G7CYP3A4TSHRDPP4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |