Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 9/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21021309 | 0.83 | LMNA (0.37) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL21021331 | 0.81 | MEN1 (0.37) | P2RX1TMPRSS4P2RX4P2RX7SLC9A1 | |
| SCHEMBL20076742 | 0.77 | MEN1 (0.31) | MEN1LMNAMAPTKMT2A | |
| SCHEMBL21022361 | 0.77 | SLC9A1 (0.33) | SLC9A1 | |
| SCHEMBL20076548 | 0.76 | POLB (0.34) | SLC9A1NPC1RAB9AMEN1MAPT | |
| SCHEMBL20076610 | 0.76 | HDAC1 (0.35) | NPC1RAB9ALMNAMAPTNR1H4 | |
| SCHEMBL21020557 | 0.75 | NPC1 (0.32) | NPC1RAB9AMEN1LMNAMAPT | |
| SCHEMBL21020695 | 0.75 | — | — | |
| SCHEMBL20076998 | 0.74 | KMT2A (0.41) | SLC9A1NPC1RAB9AMEN1LMNA | |
| SCHEMBL20076568 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |