Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BMX | P51813 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | GRK2 | P25098 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21020608 | 0.75 | MAPT (0.36) | TP53MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23465563 | 0.74 | KMT2A (0.33) | SLC9A1LMNATP53MAPTKMT2A | |
| SCHEMBL20076828 | 0.72 | SLC9A1 (0.37) | SLC9A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20076622 | 0.70 | SLC9A1 (0.35) | SLC9A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21021815 | 0.70 | ALDH1A1 (0.42) | LMNATP53MAPTKMT2AKDM4E | |
| SCHEMBL20076750 | 0.70 | SLC9A1 (0.35) | SLC9A1MAPTKMT2AALDH1A1 | |
| SCHEMBL20076501 | 0.67 | MAPT (0.33) | SLC9A1LMNATP53MAPTKMT2A | |
| SCHEMBL21021942 | 0.67 | TAS1R3 (0.46) | SLC9A1TDP1 | |
| SCHEMBL21022250 | 0.66 | BRAF (0.31) | — | |
| SCHEMBL21021227 | 0.66 | MAPT (0.35) | SLC9A1LMNATP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |