Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239729 | 0.79 | HTR2A (0.44) | KCNH2SLC6A2HTR2ASLC6A4MEN1 | |
| SCHEMBL16699619 | 0.74 | CNR2 (0.53) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL16699996 | 0.73 | CNR2 (0.52) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL8053802 | 0.72 | SIGMAR1 (0.59) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL798094 | 0.72 | HRH3 (0.58) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL21023409 | 0.71 | KCNH2 (0.43) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL14587216 | 0.70 | CNR2 (0.53) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL12201774 | 0.70 | SIGMAR1 (0.56) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL8131565 | 0.70 | MEN1 (0.49) | KCNH2LMNASLC6A2HTR2ASLC6A4 | |
| SCHEMBL13818361 | 0.70 | PYCR1 (0.44) | KCNH2LMNASLC6A2HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | claimed |
| US-6015925-A | TREATING MYCOSIS | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2000-01-18 | — | — | US | disclosed |