SCHEMBL2102350

SCHEMBL2102350

CCNCNC(C)c1ccccc1[SiH3]

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.36
SIGMAR1 Q99720 1/20 0.33
ADRB2 P07550 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2269974 0.85 SIGMAR1 (0.41) POLBSIGMAR1ADRB2TSHR
SCHEMBL2272357 0.75 TSHR (0.37) SIGMAR1ADRB2TSHR
SCHEMBL2102335 0.75 POLB (0.35) POLBSIGMAR1ADRB2TSHR
SCHEMBL234051 0.72 SIGMAR1 (0.38) POLBSIGMAR1ADRB2TSHR
SCHEMBL2267939 0.71 HTR2A (0.44) POLBSIGMAR1TSHR
SCHEMBL2100217 0.69 SIGMAR1 (0.36) SIGMAR1ADRB2TSHR
SCHEMBL2269781 0.69 SIGMAR1 (0.37) SIGMAR1TSHR
SCHEMBL15915010 0.67 TSHR (0.59) TSHR
SCHEMBL2103331 0.67 MAPT (0.33) ADRB2
SCHEMBL2273792 0.67 TAAR1 (0.52) SIGMAR1ADRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed