Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235044 | 0.79 | TSHR (0.35) | HTR2ASLC6A4CYP2D6TAAR1SLC18A2 | |
| SCHEMBL2269974 | 0.77 | SIGMAR1 (0.41) | SLC6A4CYP2D6KCNH2SIGMAR1TSHR | |
| SCHEMBL2102292 | 0.76 | TSHR (0.32) | HTR2ASLC6A4CYP2D6TSHRNFKB1 | |
| SCHEMBL3378475 | 0.75 | GABRA1 (0.50) | TSHRGABRA1GABRB2CYP3A4MEN1 | |
| SCHEMBL2402249 | 0.74 | SLC6A4 (0.50) | HTR2ASLC6A4CYP2D6KCNH2TAAR1 | |
| SCHEMBL15983857 | 0.73 | HTR2A (0.51) | HTR2ASLC6A4CYP2D6KCNH2TSHR | |
| SCHEMBL2400173 | 0.73 | HTT (0.51) | HTR2ASLC6A4CYP2D6KCNH2TAAR1 | |
| SCHEMBL15983778 | 0.73 | HTR2A (0.51) | HTR2ASLC6A4CYP2D6KCNH2TSHR | |
| SCHEMBL16254312 | 0.73 | SLC6A4 (0.44) | HTR2ASLC6A4CYP2D6KCNH2TAAR1 | |
| SCHEMBL10154250 | 0.73 | GABRA1 (0.60) | HTR2ASLC6A4CYP2D6KCNH2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404584-B2 | Method of manufacturing semiconductor device | FUJITSU LIMITED (JP) | 2013-03-26 | — | — | US | disclosed |
| US-20110207319-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | FUJITSU LIMITED (JP) | 2011-08-25 | — | — | US | disclosed |