SCHEMBL2269974

SCHEMBL2269974

CCNC(C)c1ccccc1[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.41
POLB P06746 1/20 0.40
ADRB2 P07550 2/20 0.36
TSHR P16473 1/20 0.35
ADRB1 P08588 2/20 0.33
CASR P41180 4/20 0.32
CYP3A4 P08684 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
CHRM1 P11229 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
OPRM1 P35372 2/20 0.32
DRD3 P35462 2/20 0.32
SLC6A3 Q01959 2/20 0.32
KCNH2 Q12809 2/20 0.32
CYP2D6 P10635 2/20 0.32
CHRM2 P08172 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
SMPD1 P17405 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2102350 0.85 POLB (0.36) SIGMAR1POLBADRB2TSHR
SCHEMBL234051 0.82 SIGMAR1 (0.38) SIGMAR1POLBADRB2TSHRADRB1
SCHEMBL2102335 0.80 POLB (0.35) SIGMAR1POLBADRB2TSHRCASR
SCHEMBL2100217 0.78 SIGMAR1 (0.36) SIGMAR1ADRB2TSHRADRB1
SCHEMBL2269781 0.78 SIGMAR1 (0.37) SIGMAR1TSHR
SCHEMBL20365617 0.78 ADRB2 (0.50) SIGMAR1POLBADRB2TSHRLMNA
SCHEMBL2267939 0.77 HTR2A (0.44) SIGMAR1POLBTSHRCYP3A4SLC6A2
SCHEMBL27381281 0.76 POLB (0.66) SIGMAR1POLBADRB2TSHRADRB1
SCHEMBL17029843 0.74 CA1 (0.53) SIGMAR1POLBSLC6A4OPRM1CYP2D6
SCHEMBL10244994 0.74 CA1 (0.53) SIGMAR1POLBSLC6A4OPRM1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed