SCHEMBL21023760

SCHEMBL21023760

CCC(O)CSc1ccc(SC[C@@H](O)CCl)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
CA1 P00915 6/20 0.38
CA2 P00918 6/20 0.38
CA4 P22748 6/20 0.38
CA7 P43166 6/20 0.38
CA9 Q16790 6/20 0.38
MAPT P10636 1/20 0.35
MAOA P21397 2/20 0.35
SLC6A4 P31645 3/20 0.34
BACE1 P56817 4/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21401396 0.90 ALDH1A1 (0.39) ALDH1A1GAACA1CA2CA4
SCHEMBL1496567 0.85 HPGD (0.41) ALDH1A1GAACA1CA2CA4
SCHEMBL21401367 0.84 ALDH1A1 (0.36) ALDH1A1GAACA1CA2CA4
SCHEMBL10187450 0.82 BACE1 (0.47) ALDH1A1GAACA1CA2CA4
SCHEMBL1496583 0.82 TEAD1 (0.42) ALDH1A1GAAMAPT
SCHEMBL27611935 0.81 MAOA (0.56) ALDH1A1CA1CA2CA4CA7
SCHEMBL1496511 0.80 CA1 (0.50) ALDH1A1CA1CA2CA4CA7
SCHEMBL1496667 0.80 MAOA (0.53) ALDH1A1CA1CA2CA4CA7
SCHEMBL1496561 0.80 MAOA (0.48) ALDH1A1CA1CA2CA4CA7
SCHEMBL1496761 0.78 CA1 (0.51) ALDH1A1CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3486272-A1 AROMATIC POLYTHIOL COMPOUND FOR OPTICAL MATERIAL SKC Co., Ltd. (KR) 2019-05-22 EP disclosed