Sugi Predict

Sugi Predict / Compounds / SCHEMBL1496561

SCHEMBL1496561

SCHEMBL1496561

OC(CCl)CSc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.48
▸ MAOB P27338 1/20 0.48
▸ ALDH1A1 P00352 1/20 0.44
▸ MAPK1 P28482 1/20 0.44
▸ CA1 P00915 4/20 0.44
▸ CA2 P00918 4/20 0.44
▸ CA4 P22748 4/20 0.44
▸ CA7 P43166 4/20 0.44
▸ CA9 Q16790 4/20 0.44
▸ MTNR1A P48039 3/20 0.43
▸ MTNR1B P49286 3/20 0.43
▸ FFAR1 O14842 1/20 0.42
▸ BACE1 P56817 3/20 0.41
▸ MAPT P10636 1/20 0.40
▸ PTGER1 P34995 1/20 0.39
▸ PTGFR P43088 1/20 0.39
▸ MMP2 P08253 3/20 0.38
▸ MMP3 P08254 3/20 0.38
▸ MMP9 P14780 3/20 0.38
▸ MMP13 P45452 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21401396 0.89 ALDH1A1 (0.39) MAOAMAOBALDH1A1CA1CA2
SCHEMBL916141 0.87 MAOA (0.56) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL1496687 0.84 BACE1 (0.47) ALDH1A1CA1CA2CA4CA7
SCHEMBL21401367 0.83 ALDH1A1 (0.36) MAOAALDH1A1CA1CA2CA4
SCHEMBL10187450 0.82 BACE1 (0.47) MAOAALDH1A1CA1CA2CA4
SCHEMBL1496583 0.82 TEAD1 (0.42) ALDH1A1MAPTMMP2MMP3MMP9
SCHEMBL6543393 0.81 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL1496771 0.81 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL6482093 0.81 MAOA (0.50) MAOAMAOBALDH1A1MAPK1CA1
SCHEMBL25292852 0.80 ALDH1A1 (0.39) ALDH1A1CA1CA2CA4CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12071515-B2 High dynamic range two-stage photopolymers THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-08-27 — — US disclosed
US-20230221637-A1 Holographic Recording Materials and Methods of Making Same UNIV COLORADO REGENTS (US) 2023-07-13 — — US disclosed
US-20230221637-A1 Holographic Recording Materials and Methods of Making Same UNIV COLORADO REGENTS (US) 2023-07-13 — — US disclosed
US-20230221637-A1 Holographic Recording Materials and Methods of Making Same UNIV COLORADO REGENTS (US) 2023-07-13 — — US disclosed
CN-116323555-A Composition, and optical material and lens using same 三菱瓦斯化学株式会社 2023-06-23 — — CN disclosed
CN-116034126-A Holographic recording material and preparation method thereof 科罗拉多大学评议会公司 2023-04-28 — — CN disclosed
CN-115989217-A Composition, and optical material and lens using the same 三菱瓦斯化学株式会社 2023-04-18 — — CN disclosed
WO-2021252665-A1 HOLOGRAPHIC RECORDING MATERIALS AND METHODS OF MAKING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-12-16 — — WO disclosed
WO-2021252665-A1 HOLOGRAPHIC RECORDING MATERIALS AND METHODS OF MAKING SAME THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2021-12-16 — — WO disclosed
US-20210246266-A1 HIGH DYNAMIC RANGE TWO-STAGE PHOTOPOLYMERS NATIONAL SCIENCE FOUNDATION 2021-08-12 — — US disclosed
US-7906667-B2 Method for producing optically active alcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-03-15 — — US disclosed
US-20100234629-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 — — US disclosed
US-7728179-B2 Method for producing optically active alcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-01 — — US disclosed
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 — — EP disclosed
US-20090012330-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-08 — — US disclosed
EP-1982972-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-10-22 — — EP disclosed
EP-1982973-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-10-22 — — EP disclosed
US-6995110-B2 Complex catalyst, process for producing the complex catalyst, and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-02-07 — — US disclosed
US-20040077487-A1 Complex catalyst, process for producing the complex catalyst, and process for producing alchohol derivative with the complex catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-22 — — US disclosed
EP-1380342-A1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-01-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090012330-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND ADH1A, ADH1C, ADH5 MAOA 2068/4885MAOB 1978/4885ALDH1A1 201/4885
US-20100234629-A1 METHOD FOR PRODUCING OPTICALLY ACTIVE ALCOHOL COMPOUND ADH1A, ADH1C, ADH5 MAOA 2149/4885MAOB 2059/4885ALDH1A1 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.