Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10333851 | 1.00 | ESR1 (0.52) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29121411 | 0.91 | ADRB1 (0.49) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22031056 | 0.89 | ESR1 (0.67) | ESR1ESR2SLC6A2OPRK1OPRM1 | |
| SCHEMBL28041147 | 0.89 | ESR1 (0.52) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3684825 | 0.87 | TAAR1 (0.50) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10518882 | 0.85 | ESR1 (0.51) | ESR1ESR2OPRK1OPRM1OPRD1 | |
| SCHEMBL20718701 | 0.84 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL25381540 | 0.83 | TAAR1 (0.52) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20906818 | 0.83 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3OPRK1OPRM1 | |
| SCHEMBL144607 | 0.81 | ESR1 (0.71) | ESR1ESR2SLC6A2SLC6A3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11253455-B2 | Carboxylated polyphenol derivatives and their cosmetic use | L'ORÉAL (FR) | 2022-02-22 | — | — | US | disclosed |
| US-20190151215-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | L'ORÉAL (FR) | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151215-A1 | CARBOXYLATED POLYPHENOL DERIVATIVES AND THEIR COSMETIC USE | H1-0, GLA, NQO1 | ESR1 999/4885ESR2 1027/4885SLC6A2 4654/4885 |
| US-11253455-B2 | Carboxylated polyphenol derivatives and their cosmetic use | H1-0, GLA, NQO1 | ESR1 999/4885ESR2 1027/4885SLC6A2 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.