SCHEMBL28041147

SCHEMBL28041147

CC(Cc1ccccc1)c1cccc(O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
ADRB2 P07550 5/20 0.48
ADRB1 P08588 2/20 0.47
ADRA1A P35348 2/20 0.47
MIF P14174 1/20 0.47
HTR2A P28223 1/20 0.47
HTR2B P41595 1/20 0.47
SLC6A2 P23975 3/20 0.47
SLC6A3 Q01959 3/20 0.47
TAAR1 Q96RJ0 2/20 0.47
SLC6A4 P31645 2/20 0.47
MAOA P21397 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CYP2A6 P11509 1/20 0.47
ADORA2A P29274 1/20 0.47
ADORA1 P30542 1/20 0.47
HTR1A P08908 1/20 0.45
ADRA2A P08913 1/20 0.45
ADRB3 P13945 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21023901 0.89 ESR1 (0.52) ESR1ESR2ADRB1ADRA1AMIF
SCHEMBL10333851 0.89 ESR1 (0.52) ESR1ESR2ADRB1ADRA1AMIF
SCHEMBL10456437 0.89 ESR1 (0.67) ESR1ESR2ADRB2ADRB1ADRA1A
SCHEMBL29121411 0.87 ADRB1 (0.49) ESR1ESR2ADRB2ADRB1ADRA1A
SCHEMBL28215703 0.85 ESR1 (0.51) ESR1ESR2ADRB2ADRB1ADRA1A
SCHEMBL19878437 0.84 ESR1 (0.47) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL900891 0.84 ESR1 (0.47) ESR1ESR2ADRB2ADRB1ADRB3
SCHEMBL25381540 0.83 TAAR1 (0.52) ESR1ESR2ADRB2ADRB1ADRA1A
SCHEMBL1648988 0.81 ESR1 (0.71) ESR1ESR2ADRB2ADRB1ADRA1A
SCHEMBL535702 0.80 TAAR1 (0.56) ESR1ESR2ADRB2ADRB1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116324124-A Hydrophobically modified associative thickener polymer and preparation method and application thereof 赫尔克里士有限公司 2023-06-23 CN disclosed
CN-116324123-A Hydrophobically modified associative thickener polymer and preparation method and application thereof 赫尔克里士有限公司 2023-06-23 CN disclosed
CN-103709442-B Stabilizer and composition comprising the same Double bond chemical (Shanghai) Co.,Ltd. (CN) 2016-01-06 CN disclosed