Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780763 | 0.85 | GAA (0.40) | GAANR3C2KDM4ELMNAL3MBTL1 | |
| SCHEMBL19954566 | 0.84 | NR3C1 (0.36) | NR3C1NR3C2OGAHRH3L3MBTL1 | |
| SCHEMBL21023691 | 0.84 | GAA (0.37) | NR3C1GAANR3C2OGAKDM4E | |
| SCHEMBL16805955 | 0.84 | ALOX15 (0.45) | GAANR3C2KDM4ELMNA | |
| SCHEMBL19954641 | 0.83 | NR3C1 (0.35) | NR3C1NR3C2OGAHRH3L3MBTL1 | |
| SCHEMBL21023568 | 0.83 | GAA (0.36) | NR3C1GAANR3C2OGAKDM4E | |
| SCHEMBL18164009 | 0.82 | GAA (0.39) | NR3C1GAANR3C2KDM4ELMNA | |
| SCHEMBL21024096 | 0.82 | GAA (0.44) | GAANR3C2KDM4ELMNATLR8 | |
| SCHEMBL18164107 | 0.82 | GAA (0.41) | GAANR3C2KDM4ELMNAL3MBTL1 | |
| SCHEMBL12912163 | 0.80 | GAA (0.43) | GAANR3C2KDM4ELMNATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080087-B1 | N-SUBSTITUTED PYRAZOLYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORP (US) | 2019-05-22 | — | — | EP | disclosed |