Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 3/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22560184 | 0.85 | TGFBR1 (0.38) | NR3C2TGFBR1L3MBTL1 | |
| SCHEMBL21023948 | 0.83 | NR3C1 (0.38) | NR3C1NR3C2HRH3OGAL3MBTL1 | |
| SCHEMBL19954636 | 0.83 | NR3C2 (0.39) | NR3C2HRH3TGFBR1 | |
| SCHEMBL19954566 | 0.82 | NR3C1 (0.36) | NR3C1NR3C2HRH3TGFBR1OGA | |
| SCHEMBL19953967 | 0.82 | DRD2 (0.38) | NR3C1HRH3 | |
| SCHEMBL19954631 | 0.79 | TGFBR1 (0.43) | NR3C2TGFBR1 | |
| SCHEMBL19954603 | 0.78 | TRPV4 (0.43) | NR3C1NR3C2TGFBR1 | |
| SCHEMBL19954623 | 0.76 | CYP1A2 (0.32) | TGFBR1 | |
| SCHEMBL15069885 | 0.74 | MAPK13 (0.40) | — | |
| SCHEMBL25745882 | 0.74 | MAPK13 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9914706-B2 | N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-13 | — | — | US | disclosed |