SCHEMBL21024768

SCHEMBL21024768

CCCCC1(CCCC)c2cc(C(=O)C(C)(C)O)ccc2-c2ccc(N(C)C)cc21

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 8/20 0.40
▸ HDAC3 O15379 1/20 0.36
▸ HDAC1 Q13547 1/20 0.36
▸ HDAC2 Q92769 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ SLC10A2 Q12908 5/20 0.35
▸ HDAC11 Q96DB2 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ HDAC6 Q9UBN7 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33
▸ MAPT P10636 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ CNR2 P34972 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21025023 0.84 PDK2 (0.45) PDK2
SCHEMBL21024771 0.84 PDK2 (0.34) PDK2SLC10A2ALDH1A1HSD17B10
SCHEMBL21024706 0.82 ALDH1A1 (0.44) PDK2SLC10A2ALDH1A1LMNAMAPT
SCHEMBL21024764 0.81 PDK2 (0.36) PDK2HDAC3HDAC1HDAC2ALDH1A1
SCHEMBL23805905 0.78 PDK2 (0.43) PDK2
SCHEMBL21024765 0.77 MAOA (0.39) PDK2ALDH1A1
SCHEMBL23805889 0.77 PDK2 (0.40) PDK2CYP3A4CNR2
SCHEMBL22355385 0.77 PDK2 (0.37) PDK2MAPT
SCHEMBL21024763 0.76 PDK2 (0.42) PDK2ALDH1A1LMNAMAPT
SCHEMBL21024769 0.76 ALDH1A1 (0.46) PDK2ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514135-B1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD CHANGZHOU TRONLY ADVANCED ELECTRONIC MAT CO LTD (CN) 2021-04-21 — — EP disclosed
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
EP-3514135-A1 FLUORENE PHOTOINITIATOR, PREPARATION METHOD THEREFOR, PHOTOCURABLE COMPOSITION HAVING SAME, AND USE OF SAME IN PHOTOCURING FIELD Changzhou Tronly Advanced Electronic Materials Co., Ltd. (CN) 2019-07-24 — — EP disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S PDK2 3423/4885HDAC3 4780/4885HDAC1 3893/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S PDK2 3423/4885HDAC3 4780/4885HDAC1 3893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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