SCHEMBL21024763

SCHEMBL21024763

CCCCC1(CCCC)c2cc(OC3CCCC3)ccc2-c2ccc(C(=O)C(C)(C)O)cc21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 3/20 0.42
▸ LMNA P02545 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ PARP10 Q53GL7 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.34
▸ HTT P42858 3/20 0.34
▸ PTGS1 P23219 1/20 0.34
▸ PTGS2 P35354 1/20 0.34
▸ LNPEP Q9UIQ6 2/20 0.33
▸ MAOA P21397 1/20 0.33
▸ MAOB P27338 1/20 0.33
▸ SCN1A P35498 1/20 0.33
▸ SCN2A Q99250 1/20 0.33
▸ SCN3A Q9NY46 1/20 0.33
▸ EPHX2 P34913 1/20 0.33
▸ DDX3X O00571 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21024764 0.84 PDK2 (0.36) PDK2LMNAMAPTALDH1A1
SCHEMBL21024765 0.79 MAOA (0.39) PDK2ALDH1A1HTTLNPEPMAOA
SCHEMBL21025023 0.78 PDK2 (0.45) PDK2
SCHEMBL21024768 0.76 PDK2 (0.40) PDK2LMNAMAPTALDH1A1
SCHEMBL21024771 0.76 PDK2 (0.34) PDK2ALDH1A1EPHX2
SCHEMBL23805885 0.74 CNR1 (0.39) LMNAMAPTALDH1A1HTT
SCHEMBL21024766 0.72 PDK2 (0.42) PDK2LMNAMAPTL3MBTL1ALDH1A1
SCHEMBL22355385 0.71 PDK2 (0.37) PDK2MAPTPTGS1PTGS2
SCHEMBL21024698 0.71 HRH3 (0.42) PDK2LMNAMAPTL3MBTL1ALDH1A1
SCHEMBL23805905 0.70 PDK2 (0.43) PDK2PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO , LTD. (CN) 2021-04-13 — — US disclosed
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field CHANGZHOU TRONLY NEW ELECTRONIC MATERIALS CO., LTD. (CN) 2019-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190155153-A1 Fluorene Photoinitiator, Preparation Method Therefor, Photocurable Composition Having Same, and Use of Same in Photocuring Field FAR1, AFF1, C1S PDK2 3423/4885LMNA 268/4885MAPT 3789/4885
US-10976660-B2 Fluorene photoinitiator, preparation method therefor, photocurable composition having same, and use of same in photocuring field FAR1, AFF1, C1S PDK2 3423/4885LMNA 268/4885MAPT 3789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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