Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 7/20 | 0.56 |
| ▸ | MMP2 | P08253 | 7/20 | 0.56 |
| ▸ | MMP9 | P14780 | 7/20 | 0.56 |
| ▸ | EGFR | P00533 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025307 | 0.93 | MMP1 (0.59) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL13352118 | 0.88 | ALDH1A1 (0.74) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL26215467 | 0.88 | PKM (0.62) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL15417392 | 0.87 | ALDH1A1 (0.69) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL21025305 | 0.84 | MMP1 (0.61) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL297188 | 0.81 | MEN1 (0.74) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL13352016 | 0.81 | MEN1 (0.74) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL13352117 | 0.81 | MMP1 (0.67) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL13352119 | 0.81 | KDM1A (0.68) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL13352028 | 0.79 | KDM1A (0.82) | KDM4EALDH1A1CYP3A4CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |