Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | NPC1 | O15118 | 9/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | F12 | P00748 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9606855 | 0.92 | MAOB (0.65) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL12723651 | 0.83 | MAOB (0.61) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL20106670 | 0.82 | RAB9A (0.70) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL16838624 | 0.81 | MAOB (0.65) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL28563872 | 0.80 | MAOB (0.68) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL12723220 | 0.77 | RAB9A (0.62) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL17277766 | 0.76 | MAOB (0.64) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL19695913 | 0.76 | GPR35 (0.51) | MAOBRAB9ANPC1KMT2AMEN1 | |
| SCHEMBL22340657 | 0.75 | TSHR (0.75) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16838626 | 0.73 | RAB9A (0.57) | MAOBRAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3485883-A1 | METHODS OF TREATING EYE DISEASES ASSOCIATED WITH INFLAMMATION AND VASCULAR PROLIFERATION | OccuRx Pty Ltd (AU) | 2019-05-22 | — | — | EP | disclosed |