Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 3/20 | 0.47 |
| ▸ | EDNRA | P25101 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21025698 | 0.76 | EDNRB (0.44) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Capsicodendrin SCHEMBL21026188 | 0.72 | EDNRB (0.39) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Capsicodendrin SCHEMBL29726673 | 0.72 | EDNRB (0.39) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025897 | 0.69 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025700 | 0.69 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL21025571 | 0.69 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamosmolide SCHEMBL15557098 | 0.69 | NFKB1 (0.43) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamodial SCHEMBL15557354 | 0.68 | EDNRB (0.41) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| Cinnamodial SCHEMBL20462860 | 0.68 | EDNRB (0.41) | EDNRBEDNRANFKB1STAT1NFKB2 | |
| SCHEMBL21025572 | 0.66 | EDNRB (0.37) | EDNRBEDNRANFKB1STAT1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | OHIO STATE INNOVATION FOUNDATION | 2019-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190150437-A1 | USE OF SESQUITERPENES AND THEIR ANALOGS AS GREEN INSECTICIDES FOR CONTROLLING DISEASE VECTORS AND PLANT PESTS | NOTUM, DDT, CYP51A1 | EDNRB 4560/4885EDNRA 3352/4885NFKB1 3371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.