SCHEMBL2102656

SCHEMBL2102656

CCN(CC)C(c1ccccc1[SiH3])N(CC)CC

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.36
KCNA5 P22460 2/20 0.36
KCNE1 P15382 1/20 0.36
KCNH2 Q12809 4/20 0.35
ADRA2A P08913 3/20 0.35
PGR P06401 1/20 0.35
ADRA2B P18089 1/20 0.35
HTR2A P28223 1/20 0.35
HRH1 P35367 1/20 0.35
TSHR P16473 1/20 0.32
CHRM2 P08172 2/20 0.31
HTR1A P08908 2/20 0.31
CHRM1 P11229 2/20 0.31
DRD1 P21728 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
ADRA1A P35348 2/20 0.31
OPRM1 P35372 2/20 0.31
DRD3 P35462 2/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2268932 0.82 KCNH2 (0.38) CYP2D6KCNA5KCNE1KCNH2ADRA2A
SCHEMBL2101605 0.80 CYP2D6 (0.34) CYP2D6KCNA5KCNE1KCNH2ADRA2A
SCHEMBL2270937 0.76 TSHR (0.35) CYP2D6KCNA5KCNE1KCNH2ADRA2A
SCHEMBL2101026 0.76 NISCH (0.34) KDM4EALDH1A1MAPT
SCHEMBL3316317 0.71 TSHR (0.40) TSHRALDH1A1MAPT
SCHEMBL22263204 0.71 TSHR (0.41) KCNA5KCNH2TSHRSMN1; SMN2
SCHEMBL2272345 0.71 MC4R (0.38) CYP2D6KCNH2ADRA2ATSHRCHRM2
SCHEMBL15915010 0.70 TSHR (0.59) TSHRKDM4EALDH1A1
SCHEMBL516288 0.69 SIGMAR1 (0.45) CYP2D6KCNA5KCNH2ADRA2APGR
SCHEMBL395127 0.68 MYC (0.38) CYP2D6KCNH2ADRA2APGRADRA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12384917-B1 Physical characteristics of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-08-12 US disclosed
US-11661483-B1 Syntheses of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-05-30 US disclosed
EP-2930177-B1 PREPARATION OF SILAZANE COMPOUND SHINETSU CHEMICAL CO (JP) 2018-04-25 EP disclosed
US-9416147-B2 Preparation of silazane compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-08-16 US disclosed
EP-2930177-A1 Preparation of silazane compound Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-14 EP disclosed
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-10-08 US disclosed
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-8164166-B2 Interfacial roughness reducing film, wiring layer, semiconductor device, and method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2012-04-24 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed
US-20090085170-A1 INTERFACIAL ROUGHNESS REDUCING FILM, WIRING LAYER, SEMICONDUCTOR DEVICE, AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-04-02 US disclosed
US-4448939-A SYNTHETIC RUBBERS; COATINGS; ADHESIVES AIR PRODUCTS AND CHEMICALS, INC. (US) 1984-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150284414-A1 PREPARATION OF SILAZANE COMPOUND SLTM, SKP2, BCAT2 CYP2D6 2127/4885KCNA5 1146/4885KCNE1 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.