Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1115098 | 0.81 | MAPT (0.63) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL30935799 | 0.81 | MAPT (0.63) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL27512078 | 0.80 | MAPT (0.48) | TDP1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20074352 | 0.78 | KMT2A (0.53) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL21027971 | 0.77 | BRD4 (0.56) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL21027973 | 0.77 | ALDH1A1 (0.51) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL16585812 | 0.76 | MAPT (0.60) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL27605930 | 0.76 | TDP1 (0.50) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL30955004 | 0.76 | MAPT (0.60) | TDP1LMNAKMT2ASLC6A2SLC6A3 | |
| SCHEMBL22801020 | 0.76 | TDP1 (0.57) | TDP1LMNAKMT2ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | Stingthera, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | SILICON SWAT, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | SILICON SWAT, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | TDP1 140/4885LMNA 2479/4885KMT2A 4787/4885 |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | TDP1 140/4885LMNA 2479/4885KMT2A 4787/4885 |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | STING1, IRF3, CGAS | TDP1 140/4885LMNA 2479/4885KMT2A 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.