Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21027971 | 0.85 | BRD4 (0.56) | ALDH1A1TDP1BRD4CREBBPL3MBTL1 | |
| SCHEMBL496850 | 0.79 | TRPA1 (0.49) | ALDH1A1MAPK1KMT2ARAB9ACYP1A2 | |
| SCHEMBL21027974 | 0.77 | TDP1 (0.51) | ALDH1A1TDP1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL3071594 | 0.77 | ALDH1A1 (0.51) | ALDH1A1TDP1BRD4CREBBPL3MBTL1 | |
| Potassium SCHEMBL11752328 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1BRD4CREBBPL3MBTL1 | |
| SCHEMBL9856134 | 0.76 | ALDH1A1 (0.50) | ALDH1A1TDP1BRD4CREBBPL3MBTL1 | |
| SCHEMBL25701086 | 0.75 | ALDH1A1 (0.52) | ALDH1A1TDP1BRD4CREBBPL3MBTL1 | |
| SCHEMBL28278484 | 0.75 | TRPA1 (0.50) | ALDH1A1TSHRMAPK1KMT2ARAB9A | |
| SCHEMBL7200083 | 0.74 | AHR (0.41) | ALDH1A1TDP1MAPK1KMT2ARAB9A | |
| SCHEMBL50441 | 0.73 | ALDH1A1 (0.89) | ALDH1A1TDP1L3MBTL1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | Stingthera, Inc. | 2021-01-07 | — | — | US | disclosed |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | SILICON SWAT, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | SILICON SWAT, INC. | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190161449-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | ALDH1A1 1078/4885TDP1 140/4885BRD4 3152/4885 |
| US-20210002230-A1 | OXOACRIDINYL ACETIC ACID DERIVATIVES AND METHODS OF USE | STING1, IRF3, CGAS | ALDH1A1 1078/4885TDP1 140/4885BRD4 3152/4885 |
| US-10745358-B2 | Oxoacridinyl acetic acid derivatives and methods of use | STING1, IRF3, CGAS | ALDH1A1 1078/4885TDP1 140/4885BRD4 3152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.