Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 15/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19833670 | 0.82 | PGR (0.38) | ARPGRKCNJ1KCNH2 | |
| SCHEMBL19643519 | 0.81 | AR (0.35) | ARPGR | |
| SCHEMBL19643521 | 0.81 | AR (0.35) | ARPGR | |
| SCHEMBL19833654 | 0.81 | PGR (0.39) | ARPGRKCNJ1KCNH2 | |
| SCHEMBL19833661 | 0.81 | PGR (0.39) | ARPGRKCNJ1KCNH2 | |
| SCHEMBL21029507 | 0.77 | PGR (0.45) | ARPGRKCNJ1KCNH2 | |
| SCHEMBL31680157 | 0.76 | HTR1A (0.37) | KCNH2 | |
| SCHEMBL31585416 | 0.74 | SLC6A2 (0.55) | KCNH2 | |
| SCHEMBL31498643 | 0.74 | PGR (0.45) | ARPGRKCNJ1KCNH2 | |
| SCHEMBL1980445 | 0.71 | AR (0.51) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10934278-B2 | Compounds | AUTIFONY THERAPEUTICS LIMITED (GB) | 2021-03-02 | — | — | US | disclosed |
| US-20190161479-A1 | NOVEL COMPOUNDS | AUTIFONY SRL (IT) | 2019-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10934278-B2 | Compounds | KCNA3, KCNN3, KCND3 | AR 3581/4885PGR 3901/4885GRM2 288/4885 |
| US-20190161479-A1 | NOVEL COMPOUNDS | KCNN3, KCNA3, KCND3 | AR 4286/4885PGR 4302/4885GRM2 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.